People who have PKD were born with it. PKD is almost always inherited from a parent or from both parents. People of all genders, ages, races, ethnicities and nationalities can have PKD. Men and women get PKD equally as often. If you carry the gene that causes PKD but you do not have the disease, you are called a carrier. This is possible with autosomal recessive PKD. There is no way to prevent either form of PKD. If you have PKD, you may be able to keep your kidneys working longer by following a healthy lifestyle.
Some tips for living healthy include:. About 9 out of every 10 people with PKD have the autosomal dominant form. It is also the most common inherited kidney disease. ADPKD causes cysts to form only in the kidneys and symptoms of the disease may not appear until a person is between 30 and 50 years old. ARPKD causes cysts to form in both the kidneys and the liver. Symptoms of the disease can begin even before birth and can cause life-threatening problems in infants.
ACKD is more common in people who have had kidney disease for a long time. Most problems, such as high blood pressure, pain and UTIs, can be treated with medication, although you may need to have an operation to remove any large kidney stones that develop. If the condition reaches a point where the kidneys are not able to function properly, there are 2 main treatment options:. In some cases of ADPKD in adults, where chronic kidney disease is advanced and progressing rapidly, a medication called tolvaptan can be used to slow down the formation of cysts and protect kidney function.
Some people experience kidney failure soon after the condition is diagnosed, whereas others may live the rest of their life with their kidneys working relatively well. On average, around half of people with ADPKD require treatment for kidney failure by the time they're As well as kidney failure, ADPKD can also cause a number of other potentially serious problems, such as heart attacks and strokes caused by high blood pressure, or bleeding on the brain subarachnoid haemorrhage caused by a bulge in the wall of a blood vessel in the brain brain aneurysm.
This helps scientists look for better ways to prevent and treat this condition. In a small number of PKD cases, the gene mutation developed on its own, without either parent carrying a copy of the mutated gene. In many cases, ADPKD does not cause signs or symptoms until your kidney cysts are a half inch or larger in size. Early signs of ARPKD in the womb are larger-than-normal kidneys and a smaller-than-average size baby, a condition called growth failure.
However, some people with ARPKD do not develop signs or symptoms until later in childhood or even adulthood. Researchers have not yet found a way to prevent PKD. However, you may be able to slow PKD problems caused by high blood pressure , such as kidney damage. The health care team will probably include a general practitioner and a nephrologist, a health care provider specializing in kidney health.
The sooner you know you or your child has PKD, the sooner you can keep the condition from getting worse.
Getting tested if you or your child are at risk for PKD can help you take early action. You also can take steps to help delay or prevent kidney failure. Healthy lifestyle practices such as being active, reducing stress, and quitting smoking can help. Be active for 30 minutes or more on most days. Regular physical activity can help you reduce stress, manage your weight, and control your blood pressure.
If you are not active now, ask your health care provider about how much and what type of physical activity is right for you. However, genetic testing can be useful when a person:.
About 50 percent of people with PKD will have kidney failure by age 60, and about 60 percent will have kidney failure by age People with kidney failure will need dialysis or a kidney transplant. Certain people have an increased risk of kidney failure including:. At present, there is no cure for PKD. However, a lot of research is being done. Recent studies suggest that drinking plain water throughout the day and avoiding caffeine in beverages can slow the growth of cysts.
Research is also helping us understand the genetic basis of PKD. Studies also suggest that some treatments may slow the rate of kidney disease in PKD, but further research is needed before these treatments can be used in patients. In the meantime, many supportive treatments can be done to control symptoms, help slow the growth of cysts, and help prevent or slow down the loss of kidney function in people with PKD.
These include:. The drug can be used to help slow kidney function decline in adults at risk for this type of PKD. At present, no specific diet is known to prevent cysts from developing in patients with PKD. Reducing salt intake helps control blood pressure in PKD patients who have high blood pressure. A diet low in fat and moderate in calories is recommended to maintain a healthy weight.
Speak to your doctor or a dietitian about other changes to your diet, such as avoiding caffeine. However, exercises that are potentially harmful to the kidney, such as contact sports, should be avoided. It is important not to become too dehydrated during any physical activity. PKD runs in families. It is an inherited disorder that is passed from parents to children through genes. Genes are the basic elements of heredity. At conception, children receive a set of genes from each parent.
They determine many characteristics such as hair color and eye color. Genes can also determine the likelihood of developing a disease.
A genetic disease can happen if one or both parents pass abnormal genes to a child.
0コメント